Bifidobacterium bifidum powder

Bifidobacterium Bifidum Probiotic: The Mucosal Specialist for Immune Priming & Gut Barrier Defense

Product Overview

Bifidobacterium bifidum is a pioneer probiotic strain, renowned for its exceptional ability to colonize the human intestinal mucosa and play a critical role in priming the immune system. As one of the first microbial colonizers in infants, this strain is a master at interacting with the host's immune and mucosal layers, providing a first line of defense. We supply a high-potency, clinically relevant Bifidobacterium bifidum strain, essential for formulating advanced immune and gut barrier supplements. We offer this specialized probiotic in a high-intensity specification of 200 billion CFU, ensuring a powerful dose for targeted health applications.

Technical Advantages

Our Bifidobacterium bifidum is engineered for superior host interaction and defense support:

Exceptional Mucosal Adhesion: Demonstrates a superior capacity to adhere to the intestinal mucus layer, enabling persistent colonization and forming a protective biological barrier against pathogens.

Powerful Immune Priming: Uniquely interacts with gut-associated lymphoid tissue (GALT), effectively "educating" and priming the immune system for a balanced and efficient response.

High-Intensity 200B CFU Formula: This robust potency is designed for therapeutic-grade supplements where a substantial dose is crucial for effectively colonizing the mucosal niche and exerting robust immune-modulatory effects.

Broad HMO Utilization: Efficiently metabolizes a wide array of Human Milk Oligosaccharides (HMOs), making it a cornerstone for infant gut health and a indicator of its high adaptability in the gut environment.

Competitive Exclusion: Competes directly with pathogens for binding sites and nutrients, effectively crowding out harmful microorganisms and contributing to a resilient gut ecosystem.

Application Scenarios

Bifidobacterium bifidum is uniquely positioned for advanced immune and gut defense formulations:

Immune Priming & Defense Supplements: The ideal strain for foundational immune support products, designed to strengthen the body's first line of defense in the gut.

Infant Nutrition & Formula: A critical ingredient in probiotics for infants, supporting the development of a healthy gut microbiome and robust immune system from the very start.

Gut Barrier Integrity Products: Used in advanced supplements targeting intestinal permeability ("leaky gut"), thanks to its strong mucosal adhesion and barrier-strengthening capabilities.

Synbiotic Formulations with HMOs/GOS: Perfectly suited for high-end synbiotic products that utilize specific prebiotics like Galactooligosaccharides (GOS) or HMO analogs to maximize its growth and benefits.

Product Specifications

We provide Bifidobacterium bifidum in one high-potency CFU strength for premium product development:

200 Billion CFU: A high-intensity, therapeutic-grade option engineered for advanced dietary supplements where a powerful, colonizing dose is required for foundational immune and barrier support.

Available in bulk powder. We offer comprehensive technical support for formulation and private labeling services. Contact us for a detailed technical data sheet and pricing.

Frequently Asked Questions (FAQ)

1. What are the unique benefits of Bifidobacterium bifidum?

B. bifidum is unique for its superior ability to adhere to the gut lining, its role as a key "educator" of the infant immune system, and its efficiency in utilizing HMOs from breast milk, making it a foundational strain for early-life and immune health.

2. How does B. bifidum's "immune priming" work?

By directly interacting with immune cells in the gut lining, it helps train the immune system to distinguish between friendly bacteria and harmful pathogens, promoting a balanced response and reducing the risk of overreactions.

3. Why is a 200B CFU count critical for this strain?

Given its primary role in colonizing the competitive mucosal niche and exerting direct effects on the host immune system, a high CFU count ensures that a sufficient number of viable bacteria successfully establish and exert their protective effects.

4. Is Bifidobacterium bifidum safe for newborns and infants?

Yes, it is one of the most common and earliest colonizers of the healthy infant gut and is generally recognized as safe (GRAS) for this population. It is extensively used in infant formula globally.

5. How does B. bifidum differ from B. breve in its function?

While both are crucial for infants, B. breve is noted for its broad metabolic capabilities and support for gut comfort, whereas B. bifidum is particularly distinguished by its exceptional mucosal adhesion and specialized role in immune system education.

6. What is the shelf life and recommended storage condition?

The bulk powder has a shelf life of 24 months when stored in its original sealed packaging at or below -18°C (freezer conditions). This is essential for preserving the viability and adhesive properties of this potent strain.

7. Can adults benefit from B. bifidum, or is it just for infants?

Absolutely. While vital for infants, its benefits in reinforcing the gut barrier and modulating the immune system are highly valuable for adults, especially in supporting gut integrity and a balanced immune response.

8. Is your strain non-GMO and allergen-free?

Yes, our Bifidobacterium bifidum is non-GMO project verified. The bulk biomass is free from major allergens. A Certificate of Analysis confirming the absence of gluten, soy, and dairy is provided.

9. Do you provide technical data for immune health claims?

Yes, we supply a comprehensive technical dossier to our B2B partners, which includes in-vitro data and summaries of clinical studies relevant to its immune-modulating and adhesion properties.

10. Is it compatible with other probiotics in a blend?

Yes, it can be synergistically combined with other strains. For instance, pairing it with B. longum can provide comprehensive coverage for both immune priming and gut-brain axis support, creating a powerful foundational blend.